Nitrofurantoin mono mcr
Nitrofurantoin also can cause liver damage leading to jaundice or a form of hepatitis that can be fatal. This reaction occurs most frequently in persons with a deficiency of an enzyme called glucose-6-phosphate dehydrogenase that is very important to the survival of red blood cells. Reduced red blood cell count ( anemia) by breaking red blood cells (hemolytic anemia) can occur from nitrofurantoin. The condition can become severe and is more likely to occur in people with diabetes, vitamin B deficiency, or general debilitation. Nitrofurantoin can also cause damage to the sensory nerves of the arms and legs ( peripheral neuropathy), which can cause tingling in the extremities. Unless it is recognized and treated, this delayed lung injury can result in permanent lung damage that remains even after the drug is stopped. In other individuals, lung injury may not develop until after several months or years of therapy. Symptoms include:įortunately, the symptoms usually resolve within a week if the medication is stopped. In other persons, lung injury may occur after approximately a month of treatment. The reaction can occur within hours of the start of treatment if the patient has previously received nitrofurantoin, or within a few days of starting nitrofurantoin for the first time. Nitrofurantoin can cause serious lung injury. Stomach upset also can be minimized by using a lower dose or by taking nitrofurantoin with food or milk. The macrocrystalline form (Macrodantin) appears to cause less stomach upset. What are the side effects of nitrofurantoin and ciprofloxacin? NitrofurantoinĬommon side effects of nitrofurantoin include: SLIDESHOW Bacterial Infections 101: Types, Symptoms, and Treatments See Slideshow Ciprofloxacin is used to treat infections of the skin, lungs or airways, bones, joints, and urinary tract, infectious diarrheas, anthrax patients with fever and low white blood cell counts and intra-abdominal infections, typhoid fever, cervical and urethral gonorrhea, chronic bacterial prostatitis, and acute uncomplicated cystitis. Other fluoroquinolones include levofloxacin ( Levaquin), ofloxacin (Floxin), gatifloxacin ( Tequin), norfloxacin ( Noroxin), moxifloxacin ( Avelox), and trovafloxacin ( Trovan). It stops the multiplication of bacteria by inhibiting the reproduction and repair of their genetic material (DNA). The macrocrystalline form is more slowly absorbed than the microcrystalline form and is used for patients who cannot tolerate the microcrystalline form.Ĭiprofloxacin (Cipro) is a fluoroquinolone antibiotic used to treat bacterial infections. There are three forms of nitrofurantoin: Furadantin, a microcrystalline form Macrodantin, a macrocrystalline and Macrobid, a sustained release form of macrocrystalline. Bacteria cannot survive without a cell wall or multiply without DNA. Nitrofurantoin interferes with the production of bacterial proteins, DNA, and cell walls. Coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus. Nitrofurantoin is an antibiotic specifically used for treating urinary tract infections (UTIs) caused by several types of bacteria including E. What are nitrofurantoin and ciprofloxacin? Fluoroquinolones including ciprofloxacin have been associated with serious adverse reactions such as tendinitis or tendon rupture, particularly the Achilles tendon. Side effects of ciprofloxacin that are different from nitrofurantoin include restlessness.Side effects of nitrofurantoin that are different from ciprofloxacin include itching, change in urine color, and loss of appetite.Side effects of nitrofurantoin and ciprofloxacin that are similar include headache, rash, nausea, vomiting, diarrhea, and abdominal pain.Brand names of nitrofurantoin include Macrobid, Macrodantin, and Furadantin.Ciprofloxacin is also used to treat other bacterial infections including infections of the skin, lungs or airways, bones, and joints, infectious diarrheas, anthrax patients with fever and low white blood cell counts and intra-abdominal infections, typhoid fever, cervical and urethral gonorrhea, chronic bacterial prostatitis, and acute uncomplicated cystitis.Nitrofurantoin and ciprofloxacin ( Cipro) are antibiotics used to treat urinary tract infections ( UTIs).